Jamie Yelland

I am a postdoctoral researcher at Fred Hutch in Rasi Subramaniam's lab.

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In Rasi’s lab, I study the genetic regulation of cellular protein synthesis, using CRISPR to examine thousands of genes for their ability to control the synthesis and translation of messenger RNA.

My primary expertise is in the mechanisms and regulation of translation, the cellular process through which all genetic information is translated into functional protein molecules. I have also developed an array of scientific skills, including microbial genetics, human cell culture and genetics, cryo-electron microscopy, and many modern and old-school tools for studying the biology of RNA.

I studied biochemistry at Oberlin College, then obtained a Ph.D. from the University of Texas at Austin, where I was mentored by Arlen Johnson and David Taylor.

In my postdoctoral studies, I am building a solid foundation of computational biology skills, learning to analyze and visualize high-throughput sequencing data. I have become a big fan of version control, tidy data principles, using Docker for code reproducibility, and writing almost everything using markdown, pandoc, and/or LaTeX. Plus, now I can barely type without using vim keybindings…

Latest News

Jan 09, 2025 I’m putting a website together! :rocket: I hope it is worth it. :sweat_smile:

Selected Publications

  1. 2023_nsmb.png
    A single 2’-O-methylation of ribosomal RNA gates assembly of a functional ribosome
    James N. YellandJack P. K. Bravo, Joshua J. Black, David W. Taylor, and Arlen W. Johnson
    Nature Structural & Molecular Biology, Jan 2023